In vitro drug release, mechanical performance and stability testing of a custom silicone elastomer vaginal ring releasing dapivirine and levonorgestrel

We have previously reported a multipurpose silicone elastomer vaginal ring providing sustained release of dapivirine (an antiretroviral) and levonorgestrel (a progestin) for HIV prevention and hormonal contraception. During initial development, issues arose due to reaction between the ethynyl group...

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Detalles Bibliográficos
Autores principales: Murphy, Diarmaid J., Dallal Bashi, Yahya H., McCoy, Clare F., Boyd, Peter, Brown, Leeanne, Martin, François, McMullen, Nicole, Kleinbeck, Kyle, Dangi, Bindi, Spence, Patrick, Hansraj, Bashir, Devlin, Bríd, Malcolm, R. Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804184/
https://www.ncbi.nlm.nih.gov/pubmed/35128382
http://dx.doi.org/10.1016/j.ijpx.2022.100112

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