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Humanized Mouse Models of Systemic Lupus Erythematosus: Opportunities and Challenges
Animal models have played a crucial role in the understanding of the mechanisms and treatments of human diseases; however, owing to the large differences in genetic background and disease-specific characteristics, animal models cannot fully simulate the occurrence and progression of human diseases....
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804209/ https://www.ncbi.nlm.nih.gov/pubmed/35116040 http://dx.doi.org/10.3389/fimmu.2021.816956 |