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MiR-29a Increase in Aging May Function as a Compensatory Mechanism Against Cardiac Fibrosis Through SERPINH1 Downregulation
Deregulation of microRNA (miRNA) profile has been reportedly linked to the aging process, which is a dominant risk factor for many pathologies. Among the miRNAs with documented roles in aging-related cardiac diseases, miR-18a, -21a, -22, and -29a were mainly associated with hypertrophy and/or fibros...
Autores principales: | Rusu-Nastase, Evelyn Gabriela, Lupan, Ana-Mihaela, Marinescu, Catalina Iolanda, Neculachi, Carmen Alexandra, Preda, Mihai Bogdan, Burlacu, Alexandrina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804242/ https://www.ncbi.nlm.nih.gov/pubmed/35118144 http://dx.doi.org/10.3389/fcvm.2021.810241 |
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