The type 1 cannabinoid receptor positive allosteric modulators GAT591 and GAT593 reduce spike-and-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg

Childhood absence epilepsy (CAE) is a non-convulsive seizure disorder primarily in children characterized by absence seizures. Absence seizures consist of 2.5–5 Hz spike-and-wave discharges (SWDs) detectable using electroencephalography (EEG). Current drug treatments are only partially effective and...

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Detalles Bibliográficos
Autores principales: McElroy, Dan L., Roebuck, Andrew J., Greba, Quentin, Garai, Sumanta, Brandt, Asher L., Yilmaz, Orhan, Cain, Stuart M., Snutch, Terrance P., Thakur, Ganesh A., Laprairie, Robert B., Howland, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804275/
https://www.ncbi.nlm.nih.gov/pubmed/35128516
http://dx.doi.org/10.1016/j.ibneur.2022.01.006

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