CD8(+) T-Cell Epitope Variations Suggest a Potential Antigen HLA-A2 Binding Deficiency for Spike Protein of SARS-CoV-2

We identified SARS-CoV-2 specific antigen epitopes by HLA-A2 binding affinity analysis and characterized their ability to activate T cells. As the pandemic continues, variations in SARS-CoV-2 virus strains have been found in many countries. In this study, we directly assess the immune response to SA...

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Detalles Bibliográficos
Autores principales: Qiu, Congling, Xiao, Chanchan, Wang, Zhigang, Zhu, Guodong, Mao, Lipeng, Chen, Xiongfei, Gao, Lijuan, Deng, Jieping, Su, Jun, Su, Huanxing, Fang, Evandro Fei, Zhang, Zhang-Jin, Zhang, Jikai, Xie, Caojun, Yuan, Jun, Luo, Oscar Junhong, Huang, Li`an, Wang, Pengcheng, Chen, Guobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804355/
https://www.ncbi.nlm.nih.gov/pubmed/35116022
http://dx.doi.org/10.3389/fimmu.2021.764949

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