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Experimental Periodontitis Deteriorated Atherosclerosis Associated With Trimethylamine N-Oxide Metabolism in Mice

BACKGROUND: Periodontitis is considered a risk factor for atherosclerosis, but the mechanism is not clear. It was reported that oral administration of Porphyromonas gingivalis altered the gut microbiota in mice. Gut dysbiosis and the intestinal metabolite trimethylamine N-oxide (TMAO) were verified...

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Detalles Bibliográficos
Autores principales: Xiao, Lingling, Huang, Lingyan, Zhou, Xin, Zhao, Dan, Wang, Yan, Min, Haiyan, Song, Shiyu, Sun, Weibin, Gao, Qian, Hu, Qingang, Xie, Sijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804528/
https://www.ncbi.nlm.nih.gov/pubmed/35118014
http://dx.doi.org/10.3389/fcimb.2021.820535