Aging of human hematopoietic stem cells is linked to changes in Cdc42 activity

In this study, we characterize age-related phenotypes of human hematopoietic stem cells (HSC). We report increased frequencies of HSC, hematopoietic progenitor cells and lineage negative cells in the elderly but a decreased frequency of multi-lymphoid progenitors. Aged human HSC further exhibited a...

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Detalles Bibliográficos
Autores principales: Amoah, Amanda, Keller, Anja, Emini, Ramiz, Hoenicka, Markus, Liebold, Andreas, Vollmer, Angelika, Eiwen, Karina, Soller, Karin, Sakk, Vadim, Zheng, Yi, Florian, Maria Carolina, Geiger, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804569/
https://www.ncbi.nlm.nih.gov/pubmed/33440922
http://dx.doi.org/10.3324/haematol.2020.269670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804569/
https://www.ncbi.nlm.nih.gov/pubmed/33440922
http://dx.doi.org/10.3324/haematol.2020.269670

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