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The impact of pimavanserin on psychotic phenotypes and tau phosphorylation in the P301L/COMT– and rTg(P301L)4510 mouse models of Alzheimer's disease

INTRODUCTION: Psychosis in Alzheimer's disease (AD) is associated with grave clinical consequences including a precipitous cognitive decline and a hastened demise. These outcomes are aggravated by use of existing antipsychotic medications, which are also associated with cognitive decline and in...

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Detalles Bibliográficos
Autores principales: Jimenez, Heidy, Adrien, Leslie, Wolin, Adam, Eun, John, Chang, Eric H., Burstein, Ethan S., Gomar, Jesus, Davies, Peter, Koppel, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804623/
https://www.ncbi.nlm.nih.gov/pubmed/35128032
http://dx.doi.org/10.1002/trc2.12247

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