CD4 T cell-intrinsic STING signaling controls the differentiation and effector functions of T(H)1 and T(H)9 cells

BACKGROUND: While stimulator of interferon genes (STING) activation in innate immune cells of the tumor microenvironment can result in CD8 T cell-dependent antitumor immunity, whether STING signaling affects CD4 T-cell responses remains elusive. METHODS: Here, we tested whether STING activation modu...

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Detalles Bibliográficos
Autores principales: Benoit-Lizon, Isis, Jacquin, Elise, Rivera Vargas, Thaiz, Richard, Corentin, Roussey, Aurélie, Dal Zuffo, Ludivine, Martin, Tiffany, Melis, Andréa, Vinokurova, Daria, Shahoei, Sayyed Hamed, Baeza Garcia, Alvaro, Pignol, Cassandre, Giorgiutti, Stéphane, Carapito, Raphaël, Boidot, Romain, Végran, Frédérique, Flavell, Richard A, Ryffel, Bernhard, Nelson, Eric R, Soulas-Sprauel, Pauline, Lawrence, Toby, Apetoh, Lionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804688/
https://www.ncbi.nlm.nih.gov/pubmed/35091453
http://dx.doi.org/10.1136/jitc-2021-003459

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