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Generation of cDC-like cells from human induced pluripotent stem cells via Notch signaling

BACKGROUND: Dendritic cells (DCs) play critical roles in regulating the innate and adaptive immune responses, and have long been a major focus of cancer immunotherapy. Accumulating evidence suggests that conventional type 1 DCs (cDC1s) excel in cross-presentation of exogenous antigens on MHC-I molec...

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Detalles Bibliográficos
Autores principales:	Makino, Kenichi, Long, Mark D, Kajihara, Ryutaro, Matsueda, Satoko, Oba, Takaaki, Kanehira, Kazunori, Liu, Song, Ito, Fumito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804689/ https://www.ncbi.nlm.nih.gov/pubmed/35101945 http://dx.doi.org/10.1136/jitc-2021-003827

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