Intermediate monocytes induced by IFN-γ inhibit cancer metastasis by promoting NK cell activation through FOXO1 and interleukin-27

BACKGROUND: Circulating monocytes are functionally heterogeneous and can be divided into classical (CMo), intermediate (IMo), and non-CMo/patrolling monocyte (PMo) subsets. CMo can differentiate into PMo through IMo. PMos have been shown to inhibit cancer metastasis but the role of IMo is unclear. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Rikang, Bao, Weili, Pal, Mouli, Liu, Yunfeng, Yazdanbakhsh, Karina, Zhong, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804695/
https://www.ncbi.nlm.nih.gov/pubmed/35091454
http://dx.doi.org/10.1136/jitc-2021-003539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804695/
https://www.ncbi.nlm.nih.gov/pubmed/35091454
http://dx.doi.org/10.1136/jitc-2021-003539

Ejemplares similares