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Intermediate monocytes induced by IFN-γ inhibit cancer metastasis by promoting NK cell activation through FOXO1 and interleukin-27
BACKGROUND: Circulating monocytes are functionally heterogeneous and can be divided into classical (CMo), intermediate (IMo), and non-CMo/patrolling monocyte (PMo) subsets. CMo can differentiate into PMo through IMo. PMos have been shown to inhibit cancer metastasis but the role of IMo is unclear. T...
Autores principales: | Wang, Rikang, Bao, Weili, Pal, Mouli, Liu, Yunfeng, Yazdanbakhsh, Karina, Zhong, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804695/ https://www.ncbi.nlm.nih.gov/pubmed/35091454 http://dx.doi.org/10.1136/jitc-2021-003539 |
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