Cargando…

The Safety, Clinical, and Neurophysiological Effects of Intranasal Ketamine in Patients Who Do Not Respond to Electroconvulsive Therapy: Protocol for a Pilot, Open-Label Clinical Trial

BACKGROUND: Major depressive disorder is among the most disabling illnesses worldwide, with a lifetime prevalence of 16.2%. Research suggests that 20% to 40% of patients with depression do not respond to pharmacotherapy, developing treatment-resistant depression. Electroconvulsive therapy is the gol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Knyahnytska, Yuliya, Zomorrodi, Reza, Kaster, Tyler, Voineskos, Daphne, Trevizol, Alisson, Blumberger, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JMIR Publications 2022
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804953/ https://www.ncbi.nlm.nih.gov/pubmed/34882570 http://dx.doi.org/10.2196/30163

Ejemplares similares

Neural Correlates of the DEEPP (Anti-suicidal Response to Ketamine in Treatment-Resistant Bipolar Depression) Study: Protocol for a Pilot, Open-Label Clinical Trial
por: Knyahnytska, Yuliya, et al.
Publicado: (2023)

Modulation of functional network properties in major depressive disorder following electroconvulsive therapy (ECT): a resting-state EEG analysis
por: Hill, Aron T., et al.
Publicado: (2020)

Insula H-coil deep transcranial magnetic stimulation in severe and enduring anorexia nervosa (SE-AN): a pilot study
por: Knyahnytska, Yuliya O, et al.
Publicado: (2019)

Intranasal Ketamine for Acute Pain: Behavioral and Neurophysiological Safety Analysis in Mice
por: Goswami, Nidhi, et al.
Publicado: (2021)

The Relationship Between Cortical Inhibition and Electroconvulsive Therapy in the Treatment of Major Depressive Disorder
por: Voineskos, Daphne, et al.
Publicado: (2016)

Ketamine and Electroconvulsive Therapy: Better Together?
por: Fraga, A., et al.
Publicado: (2022)

Association of Repetitive Transcranial Magnetic Stimulation Treatment With Subgenual Cingulate Hyperactivity in Patients With Major Depressive Disorder: A Secondary Analysis of a Randomized Clinical Trial
por: Hadas, Itay, et al.
Publicado: (2019)

Magnetic seizure therapy and electroconvulsive therapy increase aperiodic activity
por: Smith, Sydney E., et al.
Publicado: (2023)

Magnetic seizure therapy and electroconvulsive therapy increase aperiodic activity
por: Smith, Sydney E., et al.
Publicado: (2023)

M11. ALTERED TRANSCRANIAL MAGNETIC STIMULATION ELECTROENCEPHALOGRAPHIC MARKERS IN SCHIZOPHRENIA
por: Voineskos, Daphne, et al.
Publicado: (2020)

A comparison of intranasal ketamine and intranasal midazolam for pediatric premedication
por: Narendra, P. L., et al.
Publicado: (2015)

Biomarkers of ketamine’s antidepressant effect: a clinical review of genetics, functional connectivity, and neurophysiology
por: Alario, Alexandra A., et al.
Publicado: (2021)

Comparative Study of Intranasal Dexmedetomidine Versus Intranasal Ketamine as Premedicant in Children
por: Arun, Nidhi, et al.
Publicado: (2022)

Cognitive and Neurophysiological Recovery Following Electroconvulsive Therapy: A Study Protocol
por: Palanca, Ben J. A., et al.
Publicado: (2018)

Ketamine as the anaesthetic for electroconvulsive therapy: the KANECT randomised controlled trial
por: Fernie, Gordon, et al.
Publicado: (2017)

Dexmedetomidine vs Propofol as an Adjunct to Ketamine for Electroconvulsive Therapy Anaesthesia
por: Yeter, Tuğçe, et al.
Publicado: (2022)

Intranasal ketamine versus intranasal fentanyl on pain management in isolated traumatic patients
por: Nasr Isfahani, Mehdi, et al.
Publicado: (2022)

Effects of Nicotine on the Neurophysiological and Behavioral Effects of Ketamine in Humans
por: Mathalon, Daniel H., et al.
Publicado: (2014)

Oral and Intranasal Ketamine Use in Treatment-Resistant Catatonia: A Clinical Case Report
por: Gregor, Elizabeth, et al.
Publicado: (2023)

Predictors of remission after repetitive transcranial magnetic stimulation for the treatment of major depressive disorder: An analysis from the randomised non-inferiority THREE-D trial
por: Trevizol, Alisson P., et al.
Publicado: (2020)

Management of Treatment-Resistant Depression: Challenges and Strategies
por: Voineskos, Daphne, et al.
Publicado: (2020)

Dexmedetomidine for the management of postictal agitation after electroconvulsive therapy with S-ketamine anesthesia
por: Aksay, Suna Su, et al.
Publicado: (2017)

Electroconvulsive therapy (ECT) with ketamine induction for catatonia in an HIV positive patient
por: Nel, Yvette, et al.
Publicado: (2023)

Intranasal Dexmedetomidine Compared to a Combination of Intranasal Dexmedetomidine with Ketamine for Sedation of Children Requiring Dental Treatment: A Randomized Clinical Trial
por: Sado-Filho, Joji, et al.
Publicado: (2021)

Efficacy of intranasal ketamine and midazolam for pediatric sedation: A double-blind, randomized clinical trial
por: Khoshrang, Hossein, et al.
Publicado: (2021)

Ketamine augmentation of electroconvulsive therapy to improve neuropsychological and clinical outcomes in depression (Ketamine-ECT): a multicentre, double-blind, randomised, parallel-group, superiority trial
por: Anderson, Ian M, et al.
Publicado: (2017)

Ketamine: differential neurophysiological dynamics in functional networks in the rat brain
por: Ahnaou, A, et al.
Publicado: (2017)

Racemic Ketamine as an Alternative to Electroconvulsive Therapy for Unipolar Depression: A Randomized, Open-Label, Non-Inferiority Trial (KetECT)
por: Ekstrand, Joakim, et al.
Publicado: (2021)

Epinephrine levels decrease in responders after electroconvulsive therapy
por: Pollak, Christoph, et al.
Publicado: (2021)

A Phase II, Open-Label Clinical Trial of Intranasal Ketamine for Depression in Patients with Cancer Receiving Palliative Care (INKeD-PC Study)
por: Rosenblat, Joshua D., et al.
Publicado: (2023)

Acroagonines: Ugo Cerletti’s audacious attempt to place the neurophysiological effects of electroconvulsive therapy in vials
por: Sirgiovanni, Elisabetta
Publicado: (2022)

The Combination of Propofol and Ketamine Does Not Enhance Clinical Responses to Electroconvulsive Therapy in Major Depression—The Results From the KEOpS Study
por: Brunelin, Jerome, et al.
Publicado: (2020)

Clinical neurophysiology
por: Babu, K. Srinivasa
Publicado: (2015)

Isolating sensory artifacts in the suprathreshold TMS-EEG signal over DLPFC
por: Poorganji, Mohsen, et al.
Publicado: (2023)

Is ketamine–propofol mixture (ketofol) an appropriate alternative induction agent for electroconvulsive therapy?
por: Firouzian, Abolfazl, et al.
Publicado: (2013)

BDNF and the Antidepressant Effects of Ketamine and Propofol in Electroconvulsive Therapy: A Preliminary Study
por: Huang, Xing-Bing, et al.
Publicado: (2020)

Intranasal dexmedetomidine and intranasal ketamine association allows shorter induction time for pediatric sedation compared to intranasal dexmedetomidine and oral midazolam
por: Cossovel, Francesca, et al.
Publicado: (2022)

Comparing the analgesic effect of intranasal with intravenous ketamine in isolated orthopedic trauma: A randomized clinical trial
por: Parvizrad, Ramin, et al.
Publicado: (2017)

When Obsessive Compulsive Disorder Responds Only to Electroconvulsive Therapy: A Rare Case for Maintenance Electroconvulsive Therapy?
por: Agrawal, Adesh, et al.
Publicado: (2018)

3447 Effects of intranasal ketamine on uncontrolled cancer related pain
por: Singh, Vinita, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_bc90rb014pt5deetauqtsd39e7