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Regnase-1 Deficiency Restrains Klebsiella pneumoniae Infection by Regulation of a Type I Interferon Response

Excessive inflammation can cause tissue damage and autoimmunity, sometimes accompanied by severe morbidity or mortality. Numerous negative feedback mechanisms exist to prevent unchecked inflammation, but this restraint may come at the cost of suboptimal infection control. Regnase-1 (MCPIP1), a feedb...

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Detalles Bibliográficos
Autores principales:	Trevejo-Nuñez, Giraldina, Lin, Becky, Fan, Li, Aggor, Felix E. Y., Biswas, Partha S., Chen, Kong, Gaffen, Sarah L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805030/ https://www.ncbi.nlm.nih.gov/pubmed/35100872 http://dx.doi.org/10.1128/mbio.03792-21

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