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Lyso-Lipid-Induced Oligodendrocyte Maturation Underlies Restoration of Optic Nerve Function

Protein hyperdeimination and deficiency of lyso-phospholipids (LPC 18:1) has been associated with the pathology of demyelinating disease in both humans and mice. We uncovered interesting biology of LPC 18:1, in which LPC 18:1 induced optic nerve function restoration through oligodendrocyte maturatio...

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Detalles Bibliográficos
Autores principales: Valdivia, Anddre Osmar, Bhattacharya, Sanjoy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805197/
https://www.ncbi.nlm.nih.gov/pubmed/35027445
http://dx.doi.org/10.1523/ENEURO.0429-21.2022