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Protein Profiling of RGS6, a Pleiotropic Gene Implicated in Numerous Neuropsychiatric Disorders, Reveals Multi-Isoformic Expression and a Novel Brain-Specific Isoform

A metanalysis identified regulator of G-protein signaling 6 (RGS6) as one of 23 loci with pleiotropic effects on four or more human psychiatric disorders. This finding is significant as it confirms/extends the findings of numerous other studies implicating RGS6 in CNS function and pathology. RGS6 is...

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Detalles Bibliográficos
Autores principales: Ahlers-Dannen, K. E., Yang, J., Spicer, M. M., Maity, B., Stewart, A., Koland, J. G., Fisher, R. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805202/
https://www.ncbi.nlm.nih.gov/pubmed/34880111
http://dx.doi.org/10.1523/ENEURO.0379-21.2021