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Combinatorial nanococktails via self-assembling lipid prodrugs for synergistically overcoming drug resistance and effective cancer therapy
BACKGROUND: Combinatorial systemic chemotherapy is a powerful treatment paradigm against cancer, but it is fraught with problems due to the emergence of chemoresistance and additive systemic toxicity. In addition, coadministration of individual drugs suffers from uncontrollable pharmacokinetics and...
Autores principales: | Li, Tongyu, Shi, Weiwei, Yao, Jie, Hu, Jingyun, Sun, Qiong, Meng, Jing, Wan, Jian, Song, Haihan, Wang, Hangxiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805243/ https://www.ncbi.nlm.nih.gov/pubmed/35101154 http://dx.doi.org/10.1186/s40824-022-00249-7 |
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