Optimization of enzymatic fragmentation is crucial to maximize genome coverage: a comparison of library preparation methods for Illumina sequencing

BACKGROUND: Novel commercial kits for whole genome library preparation for next-generation sequencing on Illumina platforms promise shorter workflows, lower inputs and cost savings. Time savings are achieved by employing enzymatic DNA fragmentation and by combining end-repair and tailing reactions....

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Detalles Bibliográficos
Autores principales: Ribarska, Teodora, Bjørnstad, Pål Marius, Sundaram, Arvind Y. M., Gilfillan, Gregor D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805253/
https://www.ncbi.nlm.nih.gov/pubmed/35105301
http://dx.doi.org/10.1186/s12864-022-08316-y

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