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Vitrectomy, subretinal Tissue plasminogen activator and Intravitreal Gas for submacular haemorrhage secondary to Exudative Age-Related macular degeneration (TIGER): study protocol for a phase 3, pan-European, two-group, non-commercial, active-control, observer-masked, superiority, randomised controlled surgical trial

BACKGROUND: Neovascular (wet) age-related macular degeneration (AMD) can be associated with large submacular haemorrhage (SMH). The natural history of SMH is very poor, with typically marked and permanent loss of central vision in the affected eye. Practice surveys indicate varied management approac...

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Detalles Bibliográficos
Autores principales: Jackson, Timothy L., Bunce, Catey, Desai, Riti, Hillenkamp, Jost, Lee, Chan Ning, Lois, Noemi, Peto, Tunde, Reeves, Barnaby C., Steel, David H., Edwards, Rhiannon T., van Meurs, Jan C., Wafa, Hatem, Wang, Yanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805308/
https://www.ncbi.nlm.nih.gov/pubmed/35101110
http://dx.doi.org/10.1186/s13063-021-05966-3