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Association of MTHFD1 gene polymorphisms and maternal smoking with risk of congenital heart disease: a hospital-based case-control study

BACKGROUND: MTHFD1 gene may affect the embryonic development by elevated homocysteine levels, DNA synthesis and DNA methylation, but limited number of genetic variants of MTHFD1 gene was focused on the association with congenital heart disease (CHD). This study examined the role of MTHFD1 gene and m...

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Detalles Bibliográficos
Autores principales: Song, Xinli, Li, Qiongxuan, Diao, Jingyi, Li, Jinqi, Li, Yihuan, Zhang, Senmao, Zhao, Lijuan, Chen, Letao, Wei, Jianhui, Shu, Jing, Liu, Yiping, Sun, Mengting, Huang, Peng, Wang, Tingting, Qin, Jiabi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805321/
https://www.ncbi.nlm.nih.gov/pubmed/35100977
http://dx.doi.org/10.1186/s12884-022-04419-2

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