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Glycemic control of adult patients with type 1 diabetes mellitus in Arabian Gulf Countries; PREDICT

BACKGROUND: Optimum glycemic control is necessary to reduce and even prevent the risk of micro- and macrovascular complications of type 1 diabetes mellitus (T1DM). The main aim of this study was to assess the prevalence of T1DM patients with adequate glycemic control in 4 Arabian Gulf countries. MET...

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Autores principales: Hafidh, Khadija, Abdella, Nabila Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805329/
https://www.ncbi.nlm.nih.gov/pubmed/35101023
http://dx.doi.org/10.1186/s12902-022-00946-3
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author Hafidh, Khadija
Abdella, Nabila Ahmed
author_facet Hafidh, Khadija
Abdella, Nabila Ahmed
author_sort Hafidh, Khadija
collection PubMed
description BACKGROUND: Optimum glycemic control is necessary to reduce and even prevent the risk of micro- and macrovascular complications of type 1 diabetes mellitus (T1DM). The main aim of this study was to assess the prevalence of T1DM patients with adequate glycemic control in 4 Arabian Gulf countries. METHODS: This study was a multicenter, observational, cross-sectional disease registry. Data were collected from adult T1DM patients who were treated with insulin within 6 months prior to the study visit. RESULTS: Out of 241 patients whose data were eligible for primary endpoint analysis, 27.4% had adequate glycemic control (HbA1c < 7%). The patients’ age ranged from 18 to 64 years, and 53% were males. The mean (SD) duration of diabetes was 14.6 (9) years and the mean HbA1c was 8.11 (1.8) %. At the time of T1DM diagnosis, mean HbA1c was 10.7 (2.17) %. About 98% of the patients were normotensive and the lipid profile of patients was found to be optimal. The main variables associated with adequate glycemic control were low HbA1c at diagnosis (P < 0.001) and absence of a family history of diabetes (P = 0.002). CONCLUSIONS: We found that the glycemic control of T1DM adult patients in Kuwait, UAE, Oman and Bahrain is suboptimal. More efforts are necessary to pinpoint the causes of inadequate control in this population. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12902-022-00946-3.
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spelling pubmed-88053292022-02-03 Glycemic control of adult patients with type 1 diabetes mellitus in Arabian Gulf Countries; PREDICT Hafidh, Khadija Abdella, Nabila Ahmed BMC Endocr Disord Research BACKGROUND: Optimum glycemic control is necessary to reduce and even prevent the risk of micro- and macrovascular complications of type 1 diabetes mellitus (T1DM). The main aim of this study was to assess the prevalence of T1DM patients with adequate glycemic control in 4 Arabian Gulf countries. METHODS: This study was a multicenter, observational, cross-sectional disease registry. Data were collected from adult T1DM patients who were treated with insulin within 6 months prior to the study visit. RESULTS: Out of 241 patients whose data were eligible for primary endpoint analysis, 27.4% had adequate glycemic control (HbA1c < 7%). The patients’ age ranged from 18 to 64 years, and 53% were males. The mean (SD) duration of diabetes was 14.6 (9) years and the mean HbA1c was 8.11 (1.8) %. At the time of T1DM diagnosis, mean HbA1c was 10.7 (2.17) %. About 98% of the patients were normotensive and the lipid profile of patients was found to be optimal. The main variables associated with adequate glycemic control were low HbA1c at diagnosis (P < 0.001) and absence of a family history of diabetes (P = 0.002). CONCLUSIONS: We found that the glycemic control of T1DM adult patients in Kuwait, UAE, Oman and Bahrain is suboptimal. More efforts are necessary to pinpoint the causes of inadequate control in this population. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12902-022-00946-3. BioMed Central 2022-01-31 /pmc/articles/PMC8805329/ /pubmed/35101023 http://dx.doi.org/10.1186/s12902-022-00946-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Hafidh, Khadija
Abdella, Nabila Ahmed
Glycemic control of adult patients with type 1 diabetes mellitus in Arabian Gulf Countries; PREDICT
title Glycemic control of adult patients with type 1 diabetes mellitus in Arabian Gulf Countries; PREDICT
title_full Glycemic control of adult patients with type 1 diabetes mellitus in Arabian Gulf Countries; PREDICT
title_fullStr Glycemic control of adult patients with type 1 diabetes mellitus in Arabian Gulf Countries; PREDICT
title_full_unstemmed Glycemic control of adult patients with type 1 diabetes mellitus in Arabian Gulf Countries; PREDICT
title_short Glycemic control of adult patients with type 1 diabetes mellitus in Arabian Gulf Countries; PREDICT
title_sort glycemic control of adult patients with type 1 diabetes mellitus in arabian gulf countries; predict
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805329/
https://www.ncbi.nlm.nih.gov/pubmed/35101023
http://dx.doi.org/10.1186/s12902-022-00946-3
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