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YTHDC1 regulates distinct post-integration steps of HIV-1 replication and is important for viral infectivity

BACKGROUND: The recent discovery of the role of m(6)A methylation in the regulation of HIV-1 replication unveiled a novel layer of regulation for HIV gene expression. This epitranscriptomic modification of HIV-1 RNAs is under the dynamic control of specific writers and erasers. In addition, cytoplas...

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Detalles Bibliográficos
Autores principales: N’Da Konan, Sarah, Ségéral, Emmanuel, Bejjani, Fabienne, Bendoumou, Maryam, Ait Said, Mélissa, Gallois-Montbrun, Sarah, Emiliani, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805373/
https://www.ncbi.nlm.nih.gov/pubmed/35101069
http://dx.doi.org/10.1186/s12977-022-00589-1