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Characteristics, origin, and potential for cancer diagnostics of ultrashort plasma cell-free DNA

Current evidence suggests that plasma cell-free DNA (cfDNA) is fragmented around a mode of 166 bp. Data supporting this view has been mainly acquired through the analysis of double-stranded cfDNA. The characteristics and diagnostic potential of single-stranded and damaged double-stranded cfDNA in he...

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Detalles Bibliográficos
Autores principales: Hudecova, Irena, Smith, Christopher G., Hänsel-Hertsch, Robert, Chilamakuri, Chandra S., Morris, James A., Vijayaraghavan, Aadhitthya, Heider, Katrin, Chandrananda, Dineika, Cooper, Wendy N., Gale, Davina, Garcia-Corbacho, Javier, Pacey, Simon, Baird, Richard D., Rosenfeld, Nitzan, Mouliere, Florent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805718/
https://www.ncbi.nlm.nih.gov/pubmed/34930798
http://dx.doi.org/10.1101/gr.275691.121