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Integration of high-resolution promoter profiling assays reveals novel, cell type–specific transcription start sites across 115 human cell and tissue types

Accurate transcription start site (TSS) annotations are essential for understanding transcriptional regulation and its role in human disease. Gene collections such as GENCODE contain annotations for tens of thousands of TSSs, but not all of these annotations are experimentally validated nor do they...

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Detalles Bibliográficos
Autores principales: Moore, Jill E., Zhang, Xiao-Ou, Elhajjajy, Shaimae I., Fan, Kaili, Pratt, Henry E., Reese, Fairlie, Mortazavi, Ali, Weng, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805725/
https://www.ncbi.nlm.nih.gov/pubmed/34949670
http://dx.doi.org/10.1101/gr.275723.121

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