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Integration of high-resolution promoter profiling assays reveals novel, cell type–specific transcription start sites across 115 human cell and tissue types
Accurate transcription start site (TSS) annotations are essential for understanding transcriptional regulation and its role in human disease. Gene collections such as GENCODE contain annotations for tens of thousands of TSSs, but not all of these annotations are experimentally validated nor do they...
Autores principales: | Moore, Jill E., Zhang, Xiao-Ou, Elhajjajy, Shaimae I., Fan, Kaili, Pratt, Henry E., Reese, Fairlie, Mortazavi, Ali, Weng, Zhiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805725/ https://www.ncbi.nlm.nih.gov/pubmed/34949670 http://dx.doi.org/10.1101/gr.275723.121 |
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