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(11)C-PiB and (124)I-Antibody PET Provide Differing Estimates of Brain Amyloid-β After Therapeutic Intervention

PET imaging of amyloid-β (Aβ) has become an important component of Alzheimer disease diagnosis. (11)C-Pittsburgh compound B ((11)C-PiB) and analogs bind to fibrillar Aβ. However, levels of nonfibrillar, soluble, aggregates of Aβ appear more dynamic during disease progression and more affected by Aβ-...

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Detalles Bibliográficos
Autores principales: Meier, Silvio R., Sehlin, Dag, Roshanbin, Sahar, Falk, Victoria Lim, Saito, Takashi, Saido, Takaomi C., Neumann, Ulf, Rokka, Johanna, Eriksson, Jonas, Syvänen, Stina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805773/
https://www.ncbi.nlm.nih.gov/pubmed/34088777
http://dx.doi.org/10.2967/jnumed.121.262083