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(11)C-PiB and (124)I-Antibody PET Provide Differing Estimates of Brain Amyloid-β After Therapeutic Intervention
PET imaging of amyloid-β (Aβ) has become an important component of Alzheimer disease diagnosis. (11)C-Pittsburgh compound B ((11)C-PiB) and analogs bind to fibrillar Aβ. However, levels of nonfibrillar, soluble, aggregates of Aβ appear more dynamic during disease progression and more affected by Aβ-...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society of Nuclear Medicine
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805773/ https://www.ncbi.nlm.nih.gov/pubmed/34088777 http://dx.doi.org/10.2967/jnumed.121.262083 |