Cargando…

Interference of KLF9 relieved the development of gestational diabetes mellitus by upregulating DDAH2

Gestational diabetes mellitus (GDM) is a situation where glucose intolerance is found in pregnant women without a previous diagnosis of diabetes. The role of Kruppel-like factor 9 (KLF9) has not been investigated in GDM, which constituted the aim of our study. HTR8/SVneo cells were induced by high g...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Weixia, Wang, Huiqin, Liu, Jing, Li, Kaixia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805879/ https://www.ncbi.nlm.nih.gov/pubmed/34787071 http://dx.doi.org/10.1080/21655979.2021.2005929

Ejemplares similares

Upregulation of DDAH2 Limits Pulmonary Hypertension and Right Ventricular Hypertrophy During Chronic Hypoxia in Ddah1 Knockout Mice
por: Hannemann, Juliane, et al.
Publicado: (2020)

DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats
por: Zhu, Zhen-Dong, et al.
Publicado: (2019)

Resveratrol relieves gestational diabetes mellitus in mice through activating AMPK
por: Yao, Liangqi, et al.
Publicado: (2015)

Assessment of DDAH1 and DDAH2 Contributions to Psychiatric Disorders via In Silico Methods
por: Kozlova, Alena A., et al.
Publicado: (2022)

Sequence Variation in DDAH1 and DDAH2 Genes Is Strongly and Additively Associated with Serum ADMA Concentrations in Individuals with Type 2 Diabetes
por: Abhary, Sotoodeh, et al.
Publicado: (2010)

The Therapeutic Effect of Zuogui Wan in Gestational Diabetes Mellitus Rats
por: Wang, Yuwei, et al.
Publicado: (2014)

Assessment of the direct effects of DDAH I on tumour angiogenesis in vivo
por: Papaevangelou, Efthymia, et al.
Publicado: (2018)

Inhibition of DDAH1, but not DDAH2, results in apoptosis of a human trophoblast cell line in response to TRAIL
por: Lumicisi, B.A., et al.
Publicado: (2015)

Inhibitors of the Hydrolytic Enzyme Dimethylarginine Dimethylaminohydrolase (DDAH): Discovery, Synthesis and Development
por: Murphy, Rhys B., et al.
Publicado: (2016)

Gestational diabetes mellitus placentas exhibit epimutations at placental development genes
por: Meyrueix, Laetitia P., et al.
Publicado: (2022)

Association between variation in the genes DDAH1 and DDAH2 and hypertension among Uygur, Kazakh and Han ethnic groups in China: Associação entre variação de genes DDAH1 e DDAH2 com hipertensão nos grupos étnicos uygur, kazakh e han na China
por: Wang, Zhong, et al.
Publicado: (2016)

CircPTPRA acts as a tumor suppressor in bladder cancer by sponging miR-636 and upregulating KLF9
por: He, Qingqing, et al.
Publicado: (2019)

Association of Variability in the DDAH1, DDAH2, AGXT2 and PRMT1 Genes with Circulating ADMA Concentration in Human Whole Blood
por: Hannemann, Juliane, et al.
Publicado: (2022)

Electroacupuncture Relieves HuR/KLF9-Mediated Inflammation to Enhance Neurological Repair after Spinal Cord Injury
por: Zhang, Junfeng, et al.
Publicado: (2023)

FXR Agonist INT-747 Upregulates DDAH Expression and Enhances Insulin Sensitivity in High-Salt Fed Dahl Rats
por: Ghebremariam, Yohannes T., et al.
Publicado: (2013)

Serum miR‐195‐5p is upregulated in gestational diabetes mellitus
por: Wang, Jianping, et al.
Publicado: (2020)

Upregulation of Klotho Aggravates Insulin Resistance in Gestational Diabetes Mellitus Trophoblast Cells
por: Lin, Li, et al.
Publicado: (2022)

The effect of haptoglobin genotype on the association of asymmetric dimethylarginine and DDAH 1 polymorphism with diabetic macroangiopathy
por: Wang, Shiyun, et al.
Publicado: (2022)

KLF4-mediated upregulation of CD9 and CD81 suppresses hepatocellular carcinoma development via JNK signaling
por: Li, Yandong, et al.
Publicado: (2020)

Modulating DDAH/NOS Pathway to Discover Vasoprotective Insulin Sensitizers
por: Lai, Li, et al.
Publicado: (2016)

Evidence for a protective role for the rs805305 single nucleotide polymorphism of dimethylarginine dimethylaminohydrolase 2 (DDAH2) in septic shock through the regulation of DDAH activity
por: Lambden, Simon, et al.
Publicado: (2018)

Relationship maternal subcutaneous adipose tissue thickness and development of gestational diabetes mellitus
por: Kansu-Celik, Hatice, et al.
Publicado: (2018)

Upregulation of IL-15 in the placenta alters trophoblasts behavior contributing to gestational diabetes mellitus
por: Li, Jiaqi, et al.
Publicado: (2021)

Formyl peptide receptor‐2 is upregulated in the blood and placenta of patients with gestational diabetes mellitus
por: Ye, Wenfeng, et al.
Publicado: (2021)

Metabolite asymmetric dimethylarginine (ADMA) functions as a destabilization enhancer of SOX9 mediated by DDAH1 in osteoarthritis
por: Wu, Yizheng, et al.
Publicado: (2023)

Gestational diabetes mellitus and macrosomia predispose to diabetes in the Lebanese population
por: Ghassibe-Sabbagh, Michella, et al.
Publicado: (2019)

The Preventive Effect of Zuogui Wan on Offspring Rats' Impaired Glucose Tolerance Whose Mothers Had Gestational Diabetes Mellitus
por: Wang, Yuwei, et al.
Publicado: (2016)

The role of blood groups in the development of diabetes mellitus after gestational diabetes mellitus
por: Karagoz, Hatice, et al.
Publicado: (2015)

Gestational diabetes mellitus
por: Alfadhli, Eman M.
Publicado: (2015)

Genetic variants in PTPRD and risk of gestational diabetes mellitus
por: Chen, Ting, et al.
Publicado: (2016)

The influence of gestational diabetes mellitus (GDM) and gestational hypertension (GH) on placental morphological changes
por: Istrate-Ofiţeru, Anca-Maria, et al.
Publicado: (2020)

DDAH1 Deficiency Attenuates Endothelial Cell Cycle Progression and Angiogenesis
por: Zhang, Ping, et al.
Publicado: (2013)

DDAH1 Protects against Acetaminophen-Induced Liver Hepatoxicity in Mice
por: Shen, Xiyue, et al.
Publicado: (2022)

DDAH1 Protects against Cardiotoxin-Induced Muscle Injury and Regeneration
por: Feng, Fei, et al.
Publicado: (2023)

A Case of Diabetes Mellitus Treated with Chloral Hydrate—Relieved
por: Cross, E.
Publicado: (1877)

Pyrrolidine dithiocarbamate ameliorates endothelial dysfunction in thoracic aorta of diabetic rats by preserving vascular DDAH activity
por: Lu, Chang-Wu, et al.
Publicado: (2017)

Correction to: Upregulation of IL-15 in the placenta alters trophoblasts behavior contributing to gestational diabetes mellitus
por: Li, Jiaqi, et al.
Publicado: (2021)

The Effect of Parental Transmission of Diabetes on the Development of Gestational Diabetes Mellitus
por: Shin, Jeong-Ah, et al.
Publicado: (2010)

Fetal sex and the development of gestational diabetes mellitus in gravidae with multiple gestation pregnancies
por: Sassin, Alexa M., et al.
Publicado: (2023)

Women in India with Gestational Diabetes Mellitus Strategy (WINGS): Methodology and development of model of care for gestational diabetes mellitus (WINGS 4)
por: Kayal, Arivudainambi, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_6nf1737eoaso9g357gm1o16idu