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Kruppel like factor 10 up-regulates PDZ and LIM domain containing protein 2 via nuclear factor kappa-B pathway to inhibit proliferation and inflammatory of fibroblastoid synovial cell in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease caused by synovitis. Two genes, KLF10 (Kruppel like factor 10) and PDZ and LIM domain containing protein 2 (PDLIM2), play key roles in cell inflammation and proliferation. However, the specific roles of the two on inflammation and proliferation of R...

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Detalles Bibliográficos
Autores principales: Wang, Shan, Zha, Xuwen, Ruan, Shengting, Yao, Shoulin, Zhang, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805881/
https://www.ncbi.nlm.nih.gov/pubmed/34713769
http://dx.doi.org/10.1080/21655979.2021.1995992