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Prostate-specific membrane antigen modulates the progression of prostate cancer by regulating the synthesis of arginine and proline and the expression of androgen receptors and Fos proto-oncogenes

The expression of prostate-specific membrane antigen (PSMA) is strikingly upregulated during oncogenesis and prostate cancer (PCa) progression, but the functions of this antigen in PCa remain unclear. Here, we constructed PSMA-knockdown LNCaP and 22rv1 cell lines and performed metabonomic and transc...

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Detalles Bibliográficos
Autores principales: Hong, Xi, Mao, Liang, Xu, Luwei, Hu, Qiang, Jia, Ruipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805960/
https://www.ncbi.nlm.nih.gov/pubmed/34974814
http://dx.doi.org/10.1080/21655979.2021.2016086

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