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Protein disulfide-isomerase A3 knockdown attenuates oxidized low-density lipoprotein-induced oxidative stress, inflammation and endothelial dysfunction in human umbilical vein endothelial cells by downregulating activating transcription factor 2

Atherosclerosis is a chronic inflammatory disease implicated in oxidative stress and endothelial dysfunction. Protein disulfide-isomerase A3 (PDIA3) has been reported to regulate oxidative stress and suppress inflammation. This study aimed to explore the function of PDIA3 in atherosclerosis and the...

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Detalles Bibliográficos
Autores principales: Jia, Jing, Wang, Yueping, Huang, Ruijuan, Du, Fengxia, Shen, Xiaozhu, Yang, Qiurong, Li, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805980/
https://www.ncbi.nlm.nih.gov/pubmed/34983301
http://dx.doi.org/10.1080/21655979.2021.2018980