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Follicular T cells optimize the germinal center response to SARS-CoV-2 protein vaccination in mice

Follicular helper T (Tfh) cells promote, whereas follicular regulatory T (Tfr) cells restrain, germinal center (GC) reactions. However, the precise roles of these cells in the complex GC reaction remain poorly understood. Here, we perturb Tfh or Tfr cells after SARS-CoV-2 spike protein vaccination i...

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Detalles Bibliográficos
Autores principales:	Cavazzoni, Cecilia B., Hanson, Benjamin L., Podestà, Manuel A., Bechu, Elsa D., Clement, Rachel L., Zhang, Hengcheng, Daccache, Joe, Reyes-Robles, Tamara, Hett, Erik C., Vora, Kalpit A., Fadeyi, Olugbeminiyi O., Oslund, Rob C., Hazuda, Daria J., Sage, Peter T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Author(s). 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806144/ https://www.ncbi.nlm.nih.gov/pubmed/35139367 http://dx.doi.org/10.1016/j.celrep.2022.110399

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