Stable flow-induced expression of KLK10 inhibits endothelial inflammation and atherosclerosis

Atherosclerosis preferentially occurs in arterial regions exposed to disturbed blood flow (d-flow), while regions exposed to stable flow (s-flow) are protected. The proatherogenic and atheroprotective effects of d-flow and s-flow are mediated in part by the global changes in endothelial cell (EC) ge...

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Detalles Bibliográficos
Autores principales: Williams, Darian, Mahmoud, Marwa, Liu, Renfa, Andueza, Aitor, Kumar, Sandeep, Kang, Dong-Won, Zhang, Jiahui, Tamargo, Ian, Villa-Roel, Nicolas, Baek, Kyung-In, Lee, Hwakyoung, An, Yongjin, Zhang, Leran, Tate, Edward W, Bagchi, Pritha, Pohl, Jan, Mosnier, Laurent O, Diamandis, Eleftherios P, Mihara, Koichiro, Hollenberg, Morley D, Dai, Zhifei, Jo, Hanjoong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806187/
https://www.ncbi.nlm.nih.gov/pubmed/35014606
http://dx.doi.org/10.7554/eLife.72579

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