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MicroRNA-146a-5p enhances T helper 17 cell differentiation via decreasing a disintegrin and metalloprotease 17 level in primary sjögren’s syndrome

In clinical practice, we found that microRNA (miR)-146a-5p is significantly up-regulated in peripheral blood mononuclear cells (PBMCs) of primary sjögren’s syndrome (pSS) patients. In vitro experiments confirmed that miR-146a-5p promotes T helper 17 (Th17) cell differentiation, but the specific mech...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyan, Xin, Shaojun, Wang, Youqing, Ju, Duo, Wu, Quan, Qiu, Ye, Niu, Xuemin, Liu, Wei, Li, Jianyou, Ji, Pengtian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806215/
https://www.ncbi.nlm.nih.gov/pubmed/33446013
http://dx.doi.org/10.1080/21655979.2020.1870321