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Long non-coding RNA MCM3AP-AS1 protects chondrocytes ATDC5 and CHON-001 from IL-1β-induced inflammation via regulating miR-138-5p/SIRT1

Osteoarthritis (OA) is a chronic inflammatory joint disease. Increased apoptosis of chondrocytes contributes to cartilage degradation in OA pathogenesis. The function of lncRNA MCM3AP-AS1 in regulating the viability of chondrocytes still awaits further elaboration. In this work, MCM3AP-AS1, miR-138-...

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Detalles Bibliográficos
Autores principales: Shi, Jianming, Cao, Fuyang, Chang, Yingjian, Xin, Chaofei, Jiang, Xu, Xu, Jianzhong, Lu, Shitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806229/
https://www.ncbi.nlm.nih.gov/pubmed/33942704
http://dx.doi.org/10.1080/21655979.2021.1905247

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