Homeobox A5 activates p53 pathway to inhibit proliferation and promote apoptosis of adrenocortical carcinoma cells by inducing Aldo-Keto reductase family 1 member B10 expression

Aldo-Keto Reductase Family 1 Member B10 (AKR1B10) and Homeobox A5 (HOXA5) are both down-regulated in adrenocortical carcinoma (ACC), and HOXA5 is predicted to bind to the promoter of AKR1B10. We aimed to investigate whether HOXA5 could bind to AKR1B10 to regulate ACC cells proliferation and apoptosi...

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Detalles Bibliográficos
Autores principales: Chen, Danyan, Shen, Zhaonan, Cheng, Xi, Wang, Qi, Zhou, Junlin, Ren, Fang, Sun, Yue, Wang, Hongman, Huang, Rongxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806264/
https://www.ncbi.nlm.nih.gov/pubmed/34027794
http://dx.doi.org/10.1080/21655979.2021.1924545

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