Long non-coding RNA MALAT1 enhances the protective effect of dexmedetomidine on acute lung injury by sponging miR-135a-5p to downregulate the ratio of X-box binding proteins XBP-1S/XBP-1U

Acute lung injury (ALI) is the common and clinically severe complication. Dexmedetomidine (DEX) can protect against lipopolysaccharide (LPS)-induced ALI through anti-apoptosis, anti-inflammatory and immune regulatory actions. It is well documented that major causes of LPS-induced ALI are endoplasmic...

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Detalles Bibliográficos
Autores principales: Li, Pengyi, Gu, Lianbing, Bian, Qingming, Jiao, Dian, Xu, Zeping, Wang, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806486/
https://www.ncbi.nlm.nih.gov/pubmed/34516310
http://dx.doi.org/10.1080/21655979.2021.1967579

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