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Omarigliptin ameliorated high glucose-induced nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome activation through activating adenosine monophosphate-activated protein kinase α (AMPKα) in renal glomerular endothelial cells

Diabetic nephropathy (DN) is a complication of diabetes that induces the development of end-stage renal disease (ESRD). The pathogenesis of DN is reported to be closely related to the activation of the NOD-like receptor 3 (NLRP3) inflammasome in renal glomerular endothelial cells. Omarigliptin is a...

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Detalles Bibliográficos
Autores principales:	Li, Ling, Qian, Kelei, Sun, Yuli, Zhao, Yong, Zhou, Yun, Xue, Ying, Hong, Xinyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806494/ https://www.ncbi.nlm.nih.gov/pubmed/34338149 http://dx.doi.org/10.1080/21655979.2021.1957748

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