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Optimization of GPC3-specific chimeric antigen receptor structure and its effect on killing hepatocellular carcinoma cells

To investigate the effect of optimized GPC3-specific chimeric antigen receptor (GPC3-CAR) structure on killing hepatocellular carcinoma (HCC) cells. We constructed three lentiviral expression vectors with different CAR structures by genetic engineering and molecular cloning techniques. These three C...

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Detalles Bibliográficos
Autores principales:	Zhao, Jianfeng, Lin, Lijuan, Luo, Yihua, Cai, Qinghe, Jiang, Xiaojie, Liao, Changxi, Wei, Huimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806505/ https://www.ncbi.nlm.nih.gov/pubmed/34261411 http://dx.doi.org/10.1080/21655979.2021.1950261

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