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Anagliptin prevented interleukin 1β (IL-1β)-induced cellular senescence in vascular smooth muscle cells through increasing the expression of sirtuin1 (SIRT1)

Vascular smooth muscle cell senescence plays a pivotal role in the pathogenesis of atherosclerosis. Anagliptin is a novel dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of hyperglycemia. Recent progress indicates that DPP-4 inhibitors show a wide range of cardiovascular benefits. We hypo...

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Detalles Bibliográficos
Autores principales:	Zhao, Juan, He, Xinrong, Zuo, Mei, Li, Xinguo, Sun, Zhiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806542/ https://www.ncbi.nlm.nih.gov/pubmed/34288819 http://dx.doi.org/10.1080/21655979.2021.1948289

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