Lumican silencing alleviates tumor necrosis factor-α-induced nucleus pulposus cell inflammation and senescence by inhibiting apoptosis signal regulating kinase 1/p38 signaling pathway via inactivating Fas ligand expression

A recent study has reported that lumican (LUM) is expressed at a high level in the nucleus pulposus specimens from herniated lumbar disc, without description of the specific mechanism. This study was designed to investigate the function and mechanism of LUM in intervertebral disc degeneration (IDD)....

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Detalles Bibliográficos
Autores principales: Li, Zhenqiang, Sun, Chengfeng, Chen, Maosong, Wang, Boding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806543/
https://www.ncbi.nlm.nih.gov/pubmed/34516336
http://dx.doi.org/10.1080/21655979.2021.1973781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806543/
https://www.ncbi.nlm.nih.gov/pubmed/34516336
http://dx.doi.org/10.1080/21655979.2021.1973781

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