Carboplatin activates the cGAS-STING pathway by upregulating the TREX-1 (three prime repair exonuclease 1) expression in human melanoma

Human melanoma is a highly aggressive type of cancer, causing significant mortalities despite the advances in treatment. Carboplatin is a cisplatin analog necessary for the treatment of various cancers and can also be used to treat human melanoma. We assessed the effects and mechanisms leading to in...

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Detalles Bibliográficos
Autores principales: Ma, Zhourui, Xiong, Qianwei, Xia, Hongliang, Liu, Wei, Dai, Shu, Cai, Shizhong, Zhu, Zhenhong, Yan, Xiangming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806763/
https://www.ncbi.nlm.nih.gov/pubmed/34519260
http://dx.doi.org/10.1080/21655979.2021.1972198

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