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Ivabradine protects rats against myocardial infarction through reinforcing autophagy via inhibiting PI3K/AKT/mTOR/p70S6K pathway

Ivabradine (Iva), a heart rate reducing agent that specifically inhibits the pacemaker I(f) ionic current, has been demonstrated to be cardioprotective in many cardiovascular diseases. Autophagy is an evolutionarily conserved metabolic process that regulates cardiac homeostasis. This study is aimed...

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Detalles Bibliográficos
Autores principales: Dai, Yingnan, Chen, Yeping, Wei, Guoqian, Zha, Li, Li, Xueqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806854/
https://www.ncbi.nlm.nih.gov/pubmed/33975512
http://dx.doi.org/10.1080/21655979.2021.1925008