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Interference with lysophosphatidic acid receptor 5 ameliorates oxidized low-density lipoprotein-induced human umbilical vein endothelial cell injury by inactivating NOD-like receptor family, pyrin domain containing 3 inflammasome signaling

Endothelial cell damage induced by oxidized low-density lipoprotein (ox-LDL) plays an important role in the pathogenesis of atherosclerosis (AS). We aimed to explore the effects of lysophosphatidic acid receptor 5 (LPAR5) on ox-LDL-induced damage of human umbilical vein endothelial cells (HUVECs). A...

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Detalles Bibliográficos
Autores principales:	Xu, Ling, Xu, Chaoxiang, Lin, Xiaoxin, Lu, Huiyao, Cai, Yinlian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806909/ https://www.ncbi.nlm.nih.gov/pubmed/34662522 http://dx.doi.org/10.1080/21655979.2021.1983975

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