Apremilast mitigates interleukin (IL)-13-induced inflammatory response and mucin production in human nasal epithelial cells (hNECs)

Interleukin (IL)-13-associated inflammatory response is important for the pathogenesis of allergic rhinitis (AR). Apremilast is a phosphodiesterase-4 (PDE4) inhibitor approved for psoriasis treatment. Here, we investigated the potential effects of Apremilast against IL-13-induced injury in human nas...

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Detalles Bibliográficos
Autores principales: Liang, Jia, Zhuang, RuoXiao, Sun, XueYao, Zhang, Feng, Zou, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806939/
https://www.ncbi.nlm.nih.gov/pubmed/34607526
http://dx.doi.org/10.1080/21655979.2021.1987818

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