Solidified Reverse Micellar Solution- (SRMS-) Based Microparticles for Enhanced Oral Bioavailability and Systemic Antifungal Efficacy of Miconazole Nitrate in Immunocompromised Mice

PURPOSE: To assess the improvement in oral bioavailability and efficacy in systemic candidiasis treatment of miconazole nitrate (MN) formulations in murine models of candidiasis. METHODS: Selected formulations containing 5% of Softisan + Phospholipon 90H lipid matrix with 3% of MN (A(1)), 5% of stea...

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Detalles Bibliográficos
Autores principales: Uronnachi, Emmanuel Maduabuchi, Attama, Anthony, Kenechukwu, Franklin, Umeyor, Chukwuebuka, Gugu, Thaddeus, Nwakile, Calistus, Ikeotuonye, Chidalu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807030/
https://www.ncbi.nlm.nih.gov/pubmed/35118159
http://dx.doi.org/10.1155/2022/8930709

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