Radiation-induced neuroinflammation: a potential protective role for poly(ADP-ribose) polymerase inhibitors?

Radiotherapy (RT) plays a fundamental role in the treatment of glioblastoma (GBM). GBM are notoriously invasive and harbor a subpopulation of cells with stem-like features which exhibit upregulation of the DNA damage response (DDR) and are radioresistant. High radiation doses are therefore delivered...

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Detalles Bibliográficos
Autores principales: Gutierrez-Quintana, Rodrigo, Walker, David J, Williams, Kaye J, Forster, Duncan M, Chalmers, Anthony J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807076/
https://www.ncbi.nlm.nih.gov/pubmed/35118383
http://dx.doi.org/10.1093/noajnl/vdab190

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