Mitochondrial DNA copy number as a prognostic marker is age-dependent in adult glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most common and aggressive form of glioma. GBM frequently displays chromosome (chr) 7 gain, chr 10 loss and/or EGFR amplification (chr7+/chr10-/EGFRamp). Overall survival (OS) is 15 months after treatment. In young adults, IDH1/2 mutations are associated with lo...

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Detalles Bibliográficos
Autores principales: Sourty, Baptiste, Dardaud, Laure-Marie, Bris, Céline, Desquiret-Dumas, Valérie, Boisselier, Blandine, Basset, Laëtitia, Figarella-Branger, Dominique, Morel, Alain, Sanson, Marc, Procaccio, Vincent, Rousseau, Audrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807107/
https://www.ncbi.nlm.nih.gov/pubmed/35118384
http://dx.doi.org/10.1093/noajnl/vdab191

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