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ASCL1 and DLL3 expressions and their clinicopathological implications in surgically resected pure small cell lung cancer: A study of 247 cases from the National Cancer Center of China

OBJECTIVE: Small cell lung cancer (SCLC) is one of the most aggressive malignancies characterized by neuroendocrine (NE) differentiation. The Delta‐like protein 3 (DLL3), as a direct downstream target of ASCL1, is involved in NE differentiation and carcinogenesis of SCLC. This study aims to investig...

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Detalles Bibliográficos
Autores principales: Hu, Chunfang, Dong, Jiyan, Liu, Li, Liu, Jingbo, Sun, Xujie, Teng, Fei, Wang, Xin, Ying, Jianming, Li, Junling, Xing, Puyuan, Yang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807256/
https://www.ncbi.nlm.nih.gov/pubmed/34931456
http://dx.doi.org/10.1111/1759-7714.14249