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Preoperative electromagnetic navigation bronchoscopy‐guided one‐stage multiple‐dye localization for resection of subsolid nodules: A single‐center pilot study

BACKGROUND: Electromagnetic navigation bronchoscopy (ENB)‐guided transbronchial dye marking and video‐assisted thoracoscopic surgery (VATS) is an emerging technique that enables successful resection of multiple small subsolid pulmonary nodules. The aim of this study was to evaluate the accuracy and...

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Autores principales: Jeong, Jong Hwan, Park, Hyeongbin, Choi, Chang‐Min, Oh, Ju Hyun, Lee, Geun Dong, Kim, Dong Kwan, Hwang, Hee Sang, Jang, Se Jin, Oh, Sang Young, Kim, Mi Young, Ji, Wonjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807268/
https://www.ncbi.nlm.nih.gov/pubmed/34951133
http://dx.doi.org/10.1111/1759-7714.14283
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author Jeong, Jong Hwan
Park, Hyeongbin
Choi, Chang‐Min
Oh, Ju Hyun
Lee, Geun Dong
Kim, Dong Kwan
Hwang, Hee Sang
Jang, Se Jin
Oh, Sang Young
Kim, Mi Young
Ji, Wonjun
author_facet Jeong, Jong Hwan
Park, Hyeongbin
Choi, Chang‐Min
Oh, Ju Hyun
Lee, Geun Dong
Kim, Dong Kwan
Hwang, Hee Sang
Jang, Se Jin
Oh, Sang Young
Kim, Mi Young
Ji, Wonjun
author_sort Jeong, Jong Hwan
collection PubMed
description BACKGROUND: Electromagnetic navigation bronchoscopy (ENB)‐guided transbronchial dye marking and video‐assisted thoracoscopic surgery (VATS) is an emerging technique that enables successful resection of multiple small subsolid pulmonary nodules. The aim of this study was to evaluate the accuracy and safety of preoperative ENB‐guided transbronchial multiple dye localization for VATS resection of subsolid pulmonary nodules. METHODS: As a single‐center pilot study, we recruited patients with at least two small or subsolid pulmonary nodules. Multiple‐dye localization was performed by intraoperative ENB‐guided transbronchial injection of an indigo carmine dye. The patients underwent VATS for sublobar resection immediately after localization. The accuracy of ENB‐guided dye marking was checked. RESULTS: ENB‐guided one‐stage multiple dye localization was conducted for 18 pulmonary nodules in seven patients between September 2018 and December 2019. The mean diameter of the pulmonary nodules was 9.3 mm (range, 4–18) and the mean distance from the pleura to pulmonary nodule was 6 mm (range, 1–17 mm). ENB‐guided transbronchial multiple dye localization was successfully performed in 94.4% (17/18), and the accuracy of ENB‐guided dye marking was 88.2% (15/17). When two nodules were not seen in intraoperative fields, anatomical sublobar resection was performed. There was no conversion to thoracotomy and operative mortalities. Among the seven patients, only one patient showed mild intrabronchial bleeding but stopped spontaneously. The changes in lung function after multiple wedge resections (−1.6% to 24.8%) were tolerable level. CONCLUSIONS: ENB‐guided one‐stage transbronchial dye localization showed accurate and safe intraoperative identification of multiple subsolid pulmonary nodules. A large scale prospective clinical study is warranted.
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spelling pubmed-88072682022-02-04 Preoperative electromagnetic navigation bronchoscopy‐guided one‐stage multiple‐dye localization for resection of subsolid nodules: A single‐center pilot study Jeong, Jong Hwan Park, Hyeongbin Choi, Chang‐Min Oh, Ju Hyun Lee, Geun Dong Kim, Dong Kwan Hwang, Hee Sang Jang, Se Jin Oh, Sang Young Kim, Mi Young Ji, Wonjun Thorac Cancer Original Articles BACKGROUND: Electromagnetic navigation bronchoscopy (ENB)‐guided transbronchial dye marking and video‐assisted thoracoscopic surgery (VATS) is an emerging technique that enables successful resection of multiple small subsolid pulmonary nodules. The aim of this study was to evaluate the accuracy and safety of preoperative ENB‐guided transbronchial multiple dye localization for VATS resection of subsolid pulmonary nodules. METHODS: As a single‐center pilot study, we recruited patients with at least two small or subsolid pulmonary nodules. Multiple‐dye localization was performed by intraoperative ENB‐guided transbronchial injection of an indigo carmine dye. The patients underwent VATS for sublobar resection immediately after localization. The accuracy of ENB‐guided dye marking was checked. RESULTS: ENB‐guided one‐stage multiple dye localization was conducted for 18 pulmonary nodules in seven patients between September 2018 and December 2019. The mean diameter of the pulmonary nodules was 9.3 mm (range, 4–18) and the mean distance from the pleura to pulmonary nodule was 6 mm (range, 1–17 mm). ENB‐guided transbronchial multiple dye localization was successfully performed in 94.4% (17/18), and the accuracy of ENB‐guided dye marking was 88.2% (15/17). When two nodules were not seen in intraoperative fields, anatomical sublobar resection was performed. There was no conversion to thoracotomy and operative mortalities. Among the seven patients, only one patient showed mild intrabronchial bleeding but stopped spontaneously. The changes in lung function after multiple wedge resections (−1.6% to 24.8%) were tolerable level. CONCLUSIONS: ENB‐guided one‐stage transbronchial dye localization showed accurate and safe intraoperative identification of multiple subsolid pulmonary nodules. A large scale prospective clinical study is warranted. John Wiley & Sons Australia, Ltd 2021-12-23 2022-02 /pmc/articles/PMC8807268/ /pubmed/34951133 http://dx.doi.org/10.1111/1759-7714.14283 Text en © 2021 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Jeong, Jong Hwan
Park, Hyeongbin
Choi, Chang‐Min
Oh, Ju Hyun
Lee, Geun Dong
Kim, Dong Kwan
Hwang, Hee Sang
Jang, Se Jin
Oh, Sang Young
Kim, Mi Young
Ji, Wonjun
Preoperative electromagnetic navigation bronchoscopy‐guided one‐stage multiple‐dye localization for resection of subsolid nodules: A single‐center pilot study
title Preoperative electromagnetic navigation bronchoscopy‐guided one‐stage multiple‐dye localization for resection of subsolid nodules: A single‐center pilot study
title_full Preoperative electromagnetic navigation bronchoscopy‐guided one‐stage multiple‐dye localization for resection of subsolid nodules: A single‐center pilot study
title_fullStr Preoperative electromagnetic navigation bronchoscopy‐guided one‐stage multiple‐dye localization for resection of subsolid nodules: A single‐center pilot study
title_full_unstemmed Preoperative electromagnetic navigation bronchoscopy‐guided one‐stage multiple‐dye localization for resection of subsolid nodules: A single‐center pilot study
title_short Preoperative electromagnetic navigation bronchoscopy‐guided one‐stage multiple‐dye localization for resection of subsolid nodules: A single‐center pilot study
title_sort preoperative electromagnetic navigation bronchoscopy‐guided one‐stage multiple‐dye localization for resection of subsolid nodules: a single‐center pilot study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807268/
https://www.ncbi.nlm.nih.gov/pubmed/34951133
http://dx.doi.org/10.1111/1759-7714.14283
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