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Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA
BACKGROUND: Coronavirus disease 2019 (COVID-19)-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients 3 months after their COVID-19 diagnosis. METHODS: We analyzed data on...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807277/ https://www.ncbi.nlm.nih.gov/pubmed/35030246 http://dx.doi.org/10.1093/ndt/gfac008 |
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author | Hemmelder, Marc H Noordzij, Marlies Vart, Priya Hilbrands, Luuk B Jager, Kitty J Abrahams, Alferso C Arroyo, David Battaglia, Yuri Ekart, Robert Mallamaci, Francesca Malloney, Sharon-Rose Oliveira, Joao Rydzewski, Andrzej Sridharan, Sivakumar Vogt, Liffert Duivenvoorden, Raphaël Gansevoort, Ron T Franssen, Casper F M |
author_facet | Hemmelder, Marc H Noordzij, Marlies Vart, Priya Hilbrands, Luuk B Jager, Kitty J Abrahams, Alferso C Arroyo, David Battaglia, Yuri Ekart, Robert Mallamaci, Francesca Malloney, Sharon-Rose Oliveira, Joao Rydzewski, Andrzej Sridharan, Sivakumar Vogt, Liffert Duivenvoorden, Raphaël Gansevoort, Ron T Franssen, Casper F M |
author_sort | Hemmelder, Marc H |
collection | PubMed |
description | BACKGROUND: Coronavirus disease 2019 (COVID-19)-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients 3 months after their COVID-19 diagnosis. METHODS: We analyzed data on dialysis patients diagnosed with COVID-19 from 1 February 2020 to 31 March 2021 from the European Renal Association COVID-19 Database (ERACODA). The outcomes studied were patient survival, residence and functional and mental health status (estimated by their treating physician) 3 months after COVID-19 diagnosis. Complete follow-up data were available for 854 surviving patients. Patient characteristics associated with recovery were analyzed using logistic regression. RESULTS: In 2449 hemodialysis patients (mean ± SD age 67.5 ± 14.4 years, 62% male), survival probabilities at 3 months after COVID-19 diagnosis were 90% for nonhospitalized patients (n = 1087), 73% for patients admitted to the hospital but not to an intensive care unit (ICU) (n = 1165) and 40% for those admitted to an ICU (n = 197). Patient survival hardly decreased between 28 days and 3 months after COVID-19 diagnosis. At 3 months, 87% functioned at their pre-existent functional and 94% at their pre-existent mental level. Only few of the surviving patients were still admitted to the hospital (0.8–6.3%) or a nursing home (∼5%). A higher age and frailty score at presentation and ICU admission were associated with worse functional outcome. CONCLUSIONS: Mortality between 28 days and 3 months after COVID-19 diagnosis was low and the majority of patients who survived COVID-19 recovered to their pre-existent functional and mental health level at 3 months after diagnosis. |
format | Online Article Text |
id | pubmed-8807277 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-88072772022-02-02 Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA Hemmelder, Marc H Noordzij, Marlies Vart, Priya Hilbrands, Luuk B Jager, Kitty J Abrahams, Alferso C Arroyo, David Battaglia, Yuri Ekart, Robert Mallamaci, Francesca Malloney, Sharon-Rose Oliveira, Joao Rydzewski, Andrzej Sridharan, Sivakumar Vogt, Liffert Duivenvoorden, Raphaël Gansevoort, Ron T Franssen, Casper F M Nephrol Dial Transplant Original Article BACKGROUND: Coronavirus disease 2019 (COVID-19)-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients 3 months after their COVID-19 diagnosis. METHODS: We analyzed data on dialysis patients diagnosed with COVID-19 from 1 February 2020 to 31 March 2021 from the European Renal Association COVID-19 Database (ERACODA). The outcomes studied were patient survival, residence and functional and mental health status (estimated by their treating physician) 3 months after COVID-19 diagnosis. Complete follow-up data were available for 854 surviving patients. Patient characteristics associated with recovery were analyzed using logistic regression. RESULTS: In 2449 hemodialysis patients (mean ± SD age 67.5 ± 14.4 years, 62% male), survival probabilities at 3 months after COVID-19 diagnosis were 90% for nonhospitalized patients (n = 1087), 73% for patients admitted to the hospital but not to an intensive care unit (ICU) (n = 1165) and 40% for those admitted to an ICU (n = 197). Patient survival hardly decreased between 28 days and 3 months after COVID-19 diagnosis. At 3 months, 87% functioned at their pre-existent functional and 94% at their pre-existent mental level. Only few of the surviving patients were still admitted to the hospital (0.8–6.3%) or a nursing home (∼5%). A higher age and frailty score at presentation and ICU admission were associated with worse functional outcome. CONCLUSIONS: Mortality between 28 days and 3 months after COVID-19 diagnosis was low and the majority of patients who survived COVID-19 recovered to their pre-existent functional and mental health level at 3 months after diagnosis. Oxford University Press 2022-01-14 /pmc/articles/PMC8807277/ /pubmed/35030246 http://dx.doi.org/10.1093/ndt/gfac008 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the ERA. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Original Article Hemmelder, Marc H Noordzij, Marlies Vart, Priya Hilbrands, Luuk B Jager, Kitty J Abrahams, Alferso C Arroyo, David Battaglia, Yuri Ekart, Robert Mallamaci, Francesca Malloney, Sharon-Rose Oliveira, Joao Rydzewski, Andrzej Sridharan, Sivakumar Vogt, Liffert Duivenvoorden, Raphaël Gansevoort, Ron T Franssen, Casper F M Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA |
title | Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA |
title_full | Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA |
title_fullStr | Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA |
title_full_unstemmed | Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA |
title_short | Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA |
title_sort | recovery of dialysis patients with covid-19: health outcomes 3 months after diagnosis in eracoda |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807277/ https://www.ncbi.nlm.nih.gov/pubmed/35030246 http://dx.doi.org/10.1093/ndt/gfac008 |
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