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Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA

BACKGROUND: Coronavirus disease 2019 (COVID-19)-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients 3 months after their COVID-19 diagnosis. METHODS: We analyzed data on...

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Autores principales: Hemmelder, Marc H, Noordzij, Marlies, Vart, Priya, Hilbrands, Luuk B, Jager, Kitty J, Abrahams, Alferso C, Arroyo, David, Battaglia, Yuri, Ekart, Robert, Mallamaci, Francesca, Malloney, Sharon-Rose, Oliveira, Joao, Rydzewski, Andrzej, Sridharan, Sivakumar, Vogt, Liffert, Duivenvoorden, Raphaël, Gansevoort, Ron T, Franssen, Casper F M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807277/
https://www.ncbi.nlm.nih.gov/pubmed/35030246
http://dx.doi.org/10.1093/ndt/gfac008
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author Hemmelder, Marc H
Noordzij, Marlies
Vart, Priya
Hilbrands, Luuk B
Jager, Kitty J
Abrahams, Alferso C
Arroyo, David
Battaglia, Yuri
Ekart, Robert
Mallamaci, Francesca
Malloney, Sharon-Rose
Oliveira, Joao
Rydzewski, Andrzej
Sridharan, Sivakumar
Vogt, Liffert
Duivenvoorden, Raphaël
Gansevoort, Ron T
Franssen, Casper F M
author_facet Hemmelder, Marc H
Noordzij, Marlies
Vart, Priya
Hilbrands, Luuk B
Jager, Kitty J
Abrahams, Alferso C
Arroyo, David
Battaglia, Yuri
Ekart, Robert
Mallamaci, Francesca
Malloney, Sharon-Rose
Oliveira, Joao
Rydzewski, Andrzej
Sridharan, Sivakumar
Vogt, Liffert
Duivenvoorden, Raphaël
Gansevoort, Ron T
Franssen, Casper F M
author_sort Hemmelder, Marc H
collection PubMed
description BACKGROUND: Coronavirus disease 2019 (COVID-19)-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients 3 months after their COVID-19 diagnosis. METHODS: We analyzed data on dialysis patients diagnosed with COVID-19 from 1 February 2020 to 31 March 2021 from the European Renal Association COVID-19 Database (ERACODA). The outcomes studied were patient survival, residence and functional and mental health status (estimated by their treating physician) 3 months after COVID-19 diagnosis. Complete follow-up data were available for 854 surviving patients. Patient characteristics associated with recovery were analyzed using logistic regression. RESULTS: In 2449 hemodialysis patients (mean ± SD age 67.5 ± 14.4 years, 62% male), survival probabilities at 3 months after COVID-19 diagnosis were 90% for nonhospitalized patients (n = 1087), 73% for patients admitted to the hospital but not to an intensive care unit (ICU) (n = 1165) and 40% for those admitted to an ICU (n = 197). Patient survival hardly decreased between 28 days and 3 months after COVID-19 diagnosis. At 3 months, 87% functioned at their pre-existent functional and 94% at their pre-existent mental level. Only few of the surviving patients were still admitted to the hospital (0.8–6.3%) or a nursing home (∼5%). A higher age and frailty score at presentation and ICU admission were associated with worse functional outcome. CONCLUSIONS: Mortality between 28 days and 3 months after COVID-19 diagnosis was low and the majority of patients who survived COVID-19 recovered to their pre-existent functional and mental health level at 3 months after diagnosis.
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spelling pubmed-88072772022-02-02 Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA Hemmelder, Marc H Noordzij, Marlies Vart, Priya Hilbrands, Luuk B Jager, Kitty J Abrahams, Alferso C Arroyo, David Battaglia, Yuri Ekart, Robert Mallamaci, Francesca Malloney, Sharon-Rose Oliveira, Joao Rydzewski, Andrzej Sridharan, Sivakumar Vogt, Liffert Duivenvoorden, Raphaël Gansevoort, Ron T Franssen, Casper F M Nephrol Dial Transplant Original Article BACKGROUND: Coronavirus disease 2019 (COVID-19)-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients 3 months after their COVID-19 diagnosis. METHODS: We analyzed data on dialysis patients diagnosed with COVID-19 from 1 February 2020 to 31 March 2021 from the European Renal Association COVID-19 Database (ERACODA). The outcomes studied were patient survival, residence and functional and mental health status (estimated by their treating physician) 3 months after COVID-19 diagnosis. Complete follow-up data were available for 854 surviving patients. Patient characteristics associated with recovery were analyzed using logistic regression. RESULTS: In 2449 hemodialysis patients (mean ± SD age 67.5 ± 14.4 years, 62% male), survival probabilities at 3 months after COVID-19 diagnosis were 90% for nonhospitalized patients (n = 1087), 73% for patients admitted to the hospital but not to an intensive care unit (ICU) (n = 1165) and 40% for those admitted to an ICU (n = 197). Patient survival hardly decreased between 28 days and 3 months after COVID-19 diagnosis. At 3 months, 87% functioned at their pre-existent functional and 94% at their pre-existent mental level. Only few of the surviving patients were still admitted to the hospital (0.8–6.3%) or a nursing home (∼5%). A higher age and frailty score at presentation and ICU admission were associated with worse functional outcome. CONCLUSIONS: Mortality between 28 days and 3 months after COVID-19 diagnosis was low and the majority of patients who survived COVID-19 recovered to their pre-existent functional and mental health level at 3 months after diagnosis. Oxford University Press 2022-01-14 /pmc/articles/PMC8807277/ /pubmed/35030246 http://dx.doi.org/10.1093/ndt/gfac008 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the ERA. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Original Article
Hemmelder, Marc H
Noordzij, Marlies
Vart, Priya
Hilbrands, Luuk B
Jager, Kitty J
Abrahams, Alferso C
Arroyo, David
Battaglia, Yuri
Ekart, Robert
Mallamaci, Francesca
Malloney, Sharon-Rose
Oliveira, Joao
Rydzewski, Andrzej
Sridharan, Sivakumar
Vogt, Liffert
Duivenvoorden, Raphaël
Gansevoort, Ron T
Franssen, Casper F M
Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA
title Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA
title_full Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA
title_fullStr Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA
title_full_unstemmed Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA
title_short Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA
title_sort recovery of dialysis patients with covid-19: health outcomes 3 months after diagnosis in eracoda
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807277/
https://www.ncbi.nlm.nih.gov/pubmed/35030246
http://dx.doi.org/10.1093/ndt/gfac008
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