Cargando…

T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients

Understanding the T-cell response to SARS-CoV-2 is key in patients who lack antibody production. We demonstrate the applicability of a functional assay to measure the T-cell response in a cohort of patients with immunodeficiency.

Detalles Bibliográficos
Autores principales: Awuah, Arnold, Zamani, Ava, Tahami, Fariba, Davis, Mark, Grandjean, Louis, Buckland, Matthew, Gilmour, Kimberly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807284/
https://www.ncbi.nlm.nih.gov/pubmed/35020892
http://dx.doi.org/10.1093/cei/uxac001
_version_ 1784643638372859904
author Awuah, Arnold
Zamani, Ava
Tahami, Fariba
Davis, Mark
Grandjean, Louis
Buckland, Matthew
Gilmour, Kimberly
author_facet Awuah, Arnold
Zamani, Ava
Tahami, Fariba
Davis, Mark
Grandjean, Louis
Buckland, Matthew
Gilmour, Kimberly
author_sort Awuah, Arnold
collection PubMed
description Understanding the T-cell response to SARS-CoV-2 is key in patients who lack antibody production. We demonstrate the applicability of a functional assay to measure the T-cell response in a cohort of patients with immunodeficiency.
format Online
Article
Text
id pubmed-8807284
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-88072842022-02-02 T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients Awuah, Arnold Zamani, Ava Tahami, Fariba Davis, Mark Grandjean, Louis Buckland, Matthew Gilmour, Kimberly Clin Exp Immunol Research Articles Understanding the T-cell response to SARS-CoV-2 is key in patients who lack antibody production. We demonstrate the applicability of a functional assay to measure the T-cell response in a cohort of patients with immunodeficiency. Oxford University Press 2022-01-10 /pmc/articles/PMC8807284/ /pubmed/35020892 http://dx.doi.org/10.1093/cei/uxac001 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the British Society for Immunology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_modelThis article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)
spellingShingle Research Articles
Awuah, Arnold
Zamani, Ava
Tahami, Fariba
Davis, Mark
Grandjean, Louis
Buckland, Matthew
Gilmour, Kimberly
T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients
title T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients
title_full T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients
title_fullStr T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients
title_full_unstemmed T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients
title_short T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients
title_sort t-cell responses to sars-cov-2 in healthy controls and primary immunodeficiency patients
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807284/
https://www.ncbi.nlm.nih.gov/pubmed/35020892
http://dx.doi.org/10.1093/cei/uxac001
work_keys_str_mv AT awuaharnold tcellresponsestosarscov2inhealthycontrolsandprimaryimmunodeficiencypatients
AT zamaniava tcellresponsestosarscov2inhealthycontrolsandprimaryimmunodeficiencypatients
AT tahamifariba tcellresponsestosarscov2inhealthycontrolsandprimaryimmunodeficiencypatients
AT davismark tcellresponsestosarscov2inhealthycontrolsandprimaryimmunodeficiencypatients
AT grandjeanlouis tcellresponsestosarscov2inhealthycontrolsandprimaryimmunodeficiencypatients
AT bucklandmatthew tcellresponsestosarscov2inhealthycontrolsandprimaryimmunodeficiencypatients
AT gilmourkimberly tcellresponsestosarscov2inhealthycontrolsandprimaryimmunodeficiencypatients