Cargando…
T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients
Understanding the T-cell response to SARS-CoV-2 is key in patients who lack antibody production. We demonstrate the applicability of a functional assay to measure the T-cell response in a cohort of patients with immunodeficiency.
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807284/ https://www.ncbi.nlm.nih.gov/pubmed/35020892 http://dx.doi.org/10.1093/cei/uxac001 |
_version_ | 1784643638372859904 |
---|---|
author | Awuah, Arnold Zamani, Ava Tahami, Fariba Davis, Mark Grandjean, Louis Buckland, Matthew Gilmour, Kimberly |
author_facet | Awuah, Arnold Zamani, Ava Tahami, Fariba Davis, Mark Grandjean, Louis Buckland, Matthew Gilmour, Kimberly |
author_sort | Awuah, Arnold |
collection | PubMed |
description | Understanding the T-cell response to SARS-CoV-2 is key in patients who lack antibody production. We demonstrate the applicability of a functional assay to measure the T-cell response in a cohort of patients with immunodeficiency. |
format | Online Article Text |
id | pubmed-8807284 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-88072842022-02-02 T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients Awuah, Arnold Zamani, Ava Tahami, Fariba Davis, Mark Grandjean, Louis Buckland, Matthew Gilmour, Kimberly Clin Exp Immunol Research Articles Understanding the T-cell response to SARS-CoV-2 is key in patients who lack antibody production. We demonstrate the applicability of a functional assay to measure the T-cell response in a cohort of patients with immunodeficiency. Oxford University Press 2022-01-10 /pmc/articles/PMC8807284/ /pubmed/35020892 http://dx.doi.org/10.1093/cei/uxac001 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the British Society for Immunology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_modelThis article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) |
spellingShingle | Research Articles Awuah, Arnold Zamani, Ava Tahami, Fariba Davis, Mark Grandjean, Louis Buckland, Matthew Gilmour, Kimberly T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients |
title | T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients |
title_full | T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients |
title_fullStr | T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients |
title_full_unstemmed | T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients |
title_short | T-cell responses to SARS-CoV-2 in healthy controls and primary immunodeficiency patients |
title_sort | t-cell responses to sars-cov-2 in healthy controls and primary immunodeficiency patients |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807284/ https://www.ncbi.nlm.nih.gov/pubmed/35020892 http://dx.doi.org/10.1093/cei/uxac001 |
work_keys_str_mv | AT awuaharnold tcellresponsestosarscov2inhealthycontrolsandprimaryimmunodeficiencypatients AT zamaniava tcellresponsestosarscov2inhealthycontrolsandprimaryimmunodeficiencypatients AT tahamifariba tcellresponsestosarscov2inhealthycontrolsandprimaryimmunodeficiencypatients AT davismark tcellresponsestosarscov2inhealthycontrolsandprimaryimmunodeficiencypatients AT grandjeanlouis tcellresponsestosarscov2inhealthycontrolsandprimaryimmunodeficiencypatients AT bucklandmatthew tcellresponsestosarscov2inhealthycontrolsandprimaryimmunodeficiencypatients AT gilmourkimberly tcellresponsestosarscov2inhealthycontrolsandprimaryimmunodeficiencypatients |